Albumin
today is a popular protein that is used for functions such as
therapy, diagnosis, and also used as an excipient. The global albumin
(excipient) market includes those that are most suited for
stabilizing and protecting a drug during its many stages till it is
administered. It protects an active pharmaceutical ingredient or a
drug against degradations, aggregation, and oxidation. The excipient
is present with the drug since the drug’s formulation and protects
it during manufacturing, storage, and transportation. An excipient’s
feasibility is checked through preformulation studies that check the
interactions it has with the intended drug and the environment. An
excipient may find vast areas of usability in drug formulation and
delivery, along with the manufacture of vaccine and to provide a
medium during vaccine production.
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Albumin
is one of the most popular excipients due to its relatively stable
character which makes it easy to handle and store. One of the key
advantages of using albumin is its intrinsic stability, due to which
it can be heated to 60°C for 10 hours. This facilitates the
inactivation of viruses during drug production.
Global
Albumin Market Segmentation
The
three categories of classifying the global albumin market are
applications, type, and geography. By type, the market becomes:
Human
Serum Albumin
Bovine
Serum Albumin
Recombinant
Albumin
Human
serum albumin held the largest market share in 2013 and was worth
US$476.7 million. The bovine serum albumin segment is the second
largest, but faces restraining factors mostly concerning ethics.
There have been many protests against the alleged cruel treatment of
bovine fetuses in the process of obtaining bovine serum. Another
restraining factor is the retention of certain amount of impurities
in the albumin excipient. The issues with bovine serum albumin are
proving to be more and more serious, prompting many researchers to
search for alternatives. The fastest growing segment in the global
albumin market by type is the recombinant albumin, with a CAGR of
2.7% within the forecast period of 2014 to 2020.
The
global albumin market according to volume is segmented into:
Vaccines
Drug
formulation and delivery
Components
of medium
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The
four general regions that are identified to function in the global
albumin market are North America, Europe, Asia Pacific, and the Rest
of the World.
Overall
Market Drivers and Restraints
The
major growth-improving factors in the global albumin market are
improvements in product stability, the rapid growth of the
recombinant albumin segment, and improvements in the purification
technology of proteins. Researchers are gaining in quality and level
of access to technology, promoting a faster rate of advancement.
On
the other hand, the restraining factors in the global albumin market
are just as serious. They include the shift in preference towards the
use of chemically defined serum-free media that threatens to cut off
avenues of development in the market. Animal cruelty protesters are
also adding pressure against the bovine albumin segment, making it
difficult for the segment to grow.
Key
Companies
The
leading players in the global albumin (excipient) market include
Thermo Fisher Scientific, Sigma-Aldrich Corporation, RayBiotech Inc.,
Octapharma AG, Novozymes A/S, Mitsubishi Tanabe Pharma Corp., MedzBio
Pte. Ltd., InVitria, HiMedia Laboratories Pvt. Ltd., and CSL Behring
LLC.
The
global albumin market is currently expected to grow at a CAGR of 2.3%
through a time window of 2014 to 2020. The market was previously
valued at US$704.9 million in 2013, and according to calculations,
should reach a total worth of US$828.2 million by 2020. Improved
product stability being its primary factor of growth, the market is
set to expand itself in terms of product quality and demand.
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